宋昕玥,女, 博士,分析化学,副教授(校聘三级教授)
研究方向:肿瘤标志物的检测和诊疗一体化研究
讲授课程:承担专业必修课《临床免疫学检测技术》和《医学检验技术专业实验》;研究生课程《现代分离技术》;校必修课《创业基础》;校选修课《跟着柯南学化学》、《和柯南比推理》、《解密漫威世界黑科技》;
主要成果:
(1)主持或参加科研项目(课题)及人才计划项目情况
v 国家自然科学基金,21605068,基于中空纤维的电化学生物传感技术分离和检测miRNA一体化研究,2017/01-2019/12,20万,在研,主持
v 山东省重点研发计划,2017GGX40110,高容量、大倍率三元镍钴锰酸锂622型锂离子电池正极材料生产技术,2017/08-2020/07,25万,在研,主持
v 山东省临沂市重点研发计划,2016GG027,内置乳酸全息传感器的智能隐形眼镜的研究与应用,2016/01-2017/12,10万,已结题,主持
v 中国博士后第61批面上资助,2017M612183,上转换纳米荧光探针实现癌细胞多模式成像和诊疗一体化研究,2016.9-2018.7,在研,主持
(2) 代表性研究成果
v Xinyue Song, Zihong Yue, Tongtong Hong, Zonghua Wang, and Shusheng Zhang, Sandwich-Structured Upconversion Nanoprobes Coated with a Thin Silica Layer for Mitochondria-Targeted Cooperative Photodynamic Therapy for Solid Malignant Tumors, Anal. Chem., 2019, 91, 13, 8549-8557
v XinYue Song, Jiayu Zhang, Zihong Yue, Zonghua Wang, Zhihong Liu*, Shusheng Zhang*, Dual-activator codoped upconversion nanoprobe with core-multishell structure for in vitro and in vivo detection of hydroxyl radical, Analytical Chemistry, 2017, 89(20): 11021-11026.
v Shuzhen Yue, Xinyue Song, Weiling Song, Sai Bi*, An enzyme-free molecular catalytic device: dynamically self-assembled DNA dendrimers for in situ imaging of microRNAs in live cells, Chemical Science, 2019,10, 1651-1658.
v Tongtong Hong, Yanxialei Jiang, Zihong Yue, Xinyue Song*, Zonghua Wang*, Shusheng Zhang, Construction of multicolor upconversion nanotheranostic agent for in-situ cooperative photodynamic therapy for deep-seated malignant tumors, Frontiers in Chemistry, 2020, 8, 52.
v Zihong Yue, Tongtong Hong, Xinyue Song*, Zonghua Wang*, Construction of a targeted photodynamic nanotheranostic agent using upconversion nanoparticles coated with the ultrathin silica layer, Chem. Commun., 2018,54, 10618-10621.
v Xinyue Song, Zihong Yue, Jiayu Zhang, Yanxialei Jiang, Zonghua Wang, Shusheng Zhang*, Multicolor upconversion nanoprobe based on dual luminescence resonance energy transfer assay for simultaneous detection and bioimaging of [Ca2+]i and pHi in living cells, Chemistry A European Journal, 2018, 24, 6458-6463.
v Yawen Ding, Xinyue Song*, Juan Chen*, Analysis of Pesticide Residue in Tomatoes by Carbon Nanotubes/β-Cyclodextrin Nanocomposite Reinforced Hollow Fiber Coupled with HPLC, Journal of Food Science, 2019, 84, 1651-1659.
v XinYue Song, Juan Chen*, YanPing Shi*, Different configurations of carbon nanotubes reinforced solid-phase microextraction techniques and their applications in the environmental analysis, Trends in Analytical Chemistry, 2017, 86: 263-275.
v XinYue Song, Juan Chen*, YanPing Shi*, Electromembrane extraction based on carbon nanotubes reinforced hollow fiber for the determination of plant hormones, New Journal of Chemistry, 2015, 39(12): 9191-9199.
v Wei Ha, XinYue Song, Juan Chen, YanPing Shi*, A physical entrapment method for the preparation of carbon nanotubes reinforced macroporous adsorption resin with enhanced selective extraction performance, Nanoscale, 2015, 7(44): 18619-18627.
v XinYue Song, Wei Ha, Juan Chen*, YanPing Shi*, Application of beta-cyclodextrin-modified carbon nanotube-reinforced hollow fiber to solid-phase microextraction of plant hormones, Journal of Chromatography A, 2014, 1374: 23-30.
v Wei Ha, Jing Yu, XinYue Song, Juan Chen, YanPing Shi*, Tunable temperature-responsive supramolecular hydrogels formed by prodrugs as a codelivery system, ACS Applied Materials&Interfaces, 2014, 6(13): 10623-10630.
v XinYue Song, YanPing Shi, Juan Chen*, Carbon nanotubes reinforced hollow fiber solid phase microextraction for the determination of strychnine and brucine in urine, Talanta, 2013, 116: 188-194.
v XinYue Song, YanPing Shi, Juan Chen*, Carbon nanotubes-reinforced hollow fibre solid-phase microextraction coupled with high performance liquid chromatography for the determination of carbamate pesticides in apples, Food Chemistry, 2013, 139(1-4): 246-252.